Thank you for your question. Both Serlife (Sertraline) and Cilift (Citalopram) are what we call SSRI's, a particular group of antidepressants that have been formulated to have less of a side-effect profile than older generation antidepressants like Fluoxetine. They have also been used in some cases to manage anxiety disorders but mostly those associated with a depressive component.
As with most pharmaceuticals your body will invariably build up a tolerance to the drug, and eventually you will require higher doses of the drugs in order to achieve a similar level of effect to that which you experienced when you first began the drug.
New research has shown though that many of these drugs have little benefit over a placebo, and that they show no long-term benefit in terms of management of the underlying problem or cause of the condition and in many of the cases result in a loss of functionality at work, socially and with family.
From a functional medicine perspective I would begin by adding in an appropriate Omega 3 supplement and consider the use of a nutraceutical supplement tailored for your specific needs and that help balance the deficiencies and excesses of serotonin, dopamine, adrenalin, noradrenalin and GABA that result in the symptoms you are experiencing. Exercise is also of great benefit and activities such as yoga have been shown to be more beneficial than Sertraline in the management of psychological disorders.
If you would like more assistance on formulating a plan to manage your condition with out the reliance on pharmaceuticals please contact me on www.healthnation.co.za
Many thanks and warm regards